Molecular mechanisms of kinesin-14 motors in spindle assembly and chromosome segregation
نویسندگان
چکیده
منابع مشابه
[Kinesin-14 leaps to pole position in bipolar spindle assembly].
Formation of a mitotic spindle occurs almost effortlessly as cells cycle and is essential for chromosome segregation. Early in a cell cycle, the replication of centrosomes or spindle pole bodies at G1/S leaves mother and daughter poles in close association until forced apart into a bipolar arrangement at mitotic onset. Kinesin-like proteins (Klps) generate a variety of forces that contribute to...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2017
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.200261